Overview of Science and Mission


Archives of Publications


Selected ERC References

  1. Zhao D, Abella BS, Beiser DG, Alvarado JP, Wang H, Hamann KJ, Vanden Hoek TL, and Becker LB. Intra-arrest cooling with delayed reperfusion yields higher survival than earlier normothermic resuscitation in a mouse model of cardiac arrest. [Published online ahead of print December 18, 2007]. Resuscitation. doi:10.1016/j.resuscitation.2007.10.015.
  1. Halperin H, Paradis N, Mosesso, Jr, V, Nichol G, Sayre M, Ornato JP, Gerardi M, Nadkarni VM, Berg R, Becker L, Siegler M, Collins M, Cairns CB, Biros MH, Vanden Hoek TL and Peberdy MA.  Recommendations for implementation of community consultation and public disclosure under the Food and Drug Administration’s “Exception from Informed Consent Requirements for Emergency Research”.  A Special Report from the American Heart Association Emergency Cardiovascular Care Committee and Council on Cardiopulmonary, Perioperative and Critical Care.Circulation. 2007;116:1855-1863.
  1. Emmanuel R, Guzy RD, Loor G, Iwase H, Waypa GB, Marks JD, Vanden Hoek TL and Schumacker PT. Oxidant stress during simulated ischemia primes cardiomyocytes for cell death during reperfusion. J Biol Chem. In press.
  1. Lavani R, Chang WT, Anderson TC, Shao ZH, Wojcik K, Li CQ, Pietrowski R, Beiser DG, Idris AH, Hamann KJ, Becker LB, Vanden Hoek TL. Altering CO2 during reperfusion of ischemic cardiomyocytes modifies mitochondrial oxidant injury. Crit Care Med. 2007;35(7):1709-1716.
  1. Shao ZH, Chang WT, Chan KC, Wojcik KR, Hsu CW, Li CQ, Li J, Anderson T, Qin Y, Becker L, Hamann K, Vanden Hoek T. Hypothermia-induced cardioprotection using extended ischemia and early reperfusion cooling. Am J Physiol (Heart Circ Physiol). 2007;(292):H1995-H2003.
  1. Edelson DP, Abella BS, Kramer-Johansen J, Wik L, Myklebust H, Barry AM, Merchant RM, Vanden Hoek TL, Steen PA, Becker LB. Effects of compression depth and pre-shock pauses predict defibrillation failure during cardiac arrest.  Resuscitation. Nov 2006;71(2):137-145.
  1. Shao ZH, Hsu CW,  Chang WT,  Waypa GB,  Li J,  Li DD, Li CQ, Anderson T, Qin Y, Schumacker PT, Becker LB, Vanden Hoek TL. Cytotoxicity induced by grape seed proanthocyanidins: Role of nitric oxide. Cell Biol and Toxicol. May 2006;22(3):149-158.
  1. Idris AH, Roberts J, Caruso L, Showstark M, Layon AJ, Becker LB, Vanden Hoek, TL, Gabrielli A. Oxidant injury occurs rapidly after cardiac arrest, cardiopulmonary resuscitation, and reperfusion. Crit Care Med. 2005;33(9):2043-2048.
  1. Abella BS, Alvarado JP, Myklebust H, Edelson D, Barry A, O’Hearn N, Vanden Hoek TL, and Becker LB. Quality of cardiopulmonary resuscitation during in-hospital cardiac arrest. JAMA. 2005;293(3):305-310.
  1. Qin Y *, Vanden Hoek TL *, Wojcik K, Anderson T, Li C-Q, Shao ZH, Becker LB and Hamann KJ. Caspase-dependent cytochrome c release and cell death in chick cardiomyocytes following simulated ischemia-reperfusion. Am J Physiol (Heart Circ Physiol). 2004;286(6):H2280-H2286.
  1. Nolan JP, Morley PT, Vanden Hoek TL, Hickey RW, ALS Task Force. Therapeutic hypothermia after cardiac arrest.  An advisory statement by the Advanced Life Support Task Force of the International Liaison Committee on Resuscitation. Circulation. 2003;108:118-121.
  1. Vanden Hoek, TL *, Qin,Y *, Wojcik K, Li, CQ, Shao, ZH, Anderson, T, Becker, LB, Hamann, KJ. Reperfusion, not simulated ischemia, initiates intrinsic apoptosis injury in chick cardiomyocytes. Am J Physiol (Heart Circ Physiol). 2003;284(1): H141-H150.
  1. Anderson T, Vanden TL. Preconditioning and the oxidants of sudden death.  Curr Opin Crit Care. 2002;3(4):194-198.
  1. Vanden Hoek TL, Becker LB, Shao Z,Li C, and Schumacker PT. Reactive oxygen species released from mitochondria during brief hypoxia induce preconditioning in cardiomyocytes. J Biol Chem. 1998;273(29):18092-18098.
  1. Vanden Hoek TL, Shao Z, Li C, Zak R, Schumacker PT, and Becker LB. Reperfusion injury on cardiac myocytes after simulated ischemia. Am J Physiol. 1996;270(4):H1334-H1341.